Lapatinib
Product Specifications
CAS Number
231277-92-2
Synonyms
GSK572016, GW2016
Target
EGFR
Applications
Protein Tyrosine Kinase
Smiles
CS (=O) (=O) CCNCC1=CC=C (O1) C2=CC3=C (C=C2) N=CN=C3NC4=CC (=C (C=C4) OCC5=CC (=CC=C5) F) Cl
Molecular Formula
C29H26ClFN4O4S
Additionnal Information
Lapatinib is a potent EGFR and ErbB2 inhibitor with IC50 of 10.8 and 9.2 nM in cell-free assays, respectively. Lapatinib induces ferroptosis and autophagic cell death.
Storage Conditions
2 years -80 in solvent
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