PF-573228

Product Specifications

CAS Number

869288-64-2

Target

FAK

Applications

Protein Tyrosine Kinase

Smiles

CS (=O) (=O) C1=CC=CC (=C1) CNC2=NC (=NC=C2C (F) (F) F) NC3=CC4=C (C=C3) NC (=O) CC4

Molecular Formula

C22H20F3N5O3S

Additionnal Information

PF-573228 is an ATP-competitive inhibitor of FAK with IC50 of 4 nM in a cell-free assay, ~50- to 250-fold selective for FAK than Pyk2, CDK1/7 and GSK-3β. PF-573228 induces apoptosis.

Storage Conditions

2 years -80 in solvent

More Discoveries

Explore Other Products

Browse additional items from our catalog

IHUPKM2KT 1 Each

Human Pyruvate Kinase Muscle ELISA Kit

View Details

E45R32112G-4 50 µL

CHRNA3 Antibody (N-term)

View Details

SI006822B 1 Each

Human H2BC1 Pre-designed siRNA Set B

View Details

MBS6330899-01 0.1 mL

PARP1, Phosphorylated (S372) (PARP1, ADPRT, PPOL, Poly [ADP-ribose] polymerase 1, ADP-ribosyltransferase diphtheria toxin-like 1, NAD(+) ADP-ribosyltransferase 1, Poly[ADP-ribose] synthase 1) (MaxLight 750)

View Details

MBS6330899-02 5x 0.1 mL

PARP1, Phosphorylated (S372) (PARP1, ADPRT, PPOL, Poly [ADP-ribose] polymerase 1, ADP-ribosyltransferase diphtheria toxin-like 1, NAD(+) ADP-ribosyltransferase 1, Poly[ADP-ribose] synthase 1) (MaxLight 750)

View Details

sc-56107 AC 500 µg/mL - 25% ag

GADD 153 (9C8) AC

View Details