PF-573228
Product Specifications
CAS Number
869288-64-2
Target
FAK
Applications
Protein Tyrosine Kinase
Smiles
CS (=O) (=O) C1=CC=CC (=C1) CNC2=NC (=NC=C2C (F) (F) F) NC3=CC4=C (C=C3) NC (=O) CC4
Molecular Formula
C22H20F3N5O3S
Additionnal Information
PF-573228 is an ATP-competitive inhibitor of FAK with IC50 of 4 nM in a cell-free assay, ~50- to 250-fold selective for FAK than Pyk2, CDK1/7 and GSK-3β. PF-573228 induces apoptosis.
Storage Conditions
2 years -80 in solvent
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