PCI-34051
Product Specifications
CAS Number
950762-95-5
Target
HDAC
Applications
DNA Damage/DNA Repair
Smiles
COC1=CC=C (C=C1) CN2C=CC3=C2C=C (C=C3) C (=O) NO
Molecular Formula
C17H16N2O3
Additionnal Information
PCI-34051 is a potent and specific HDAC8 inhibitor with IC50 of 10 nM in a cell-free assay. It has greater than 200-fold selectivity over HDAC1 and 6, more than 1000-fold selectivity over HDAC2, 3, and 10. PCI-34051 induces caspase-dependent apoptosis.
Storage Conditions
2 years -80 in solvent
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