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Indirubin-3'-monoxime

Product Specifications

CAS Number

160807-49-8

Synonyms

Indirubin-3'-oxime

Target

CDK

Applications

Cell Cycle

Smiles

C1=CC=C2C (=C1) C (=C (N2) O) C3=C (C4=CC=CC=C4N3) N=O

Molecular Formula

C16H11N3O2

Additionnal Information

Indirubin-3'-monoxime (Indirubin-3'-oxime) is a selective CDK inhibitor with IC50 of 0.18 μM, 0.44 μM, 0.25 μM, 3.33 μM, 0.065 μM for CDK1-cyclinB, CDK2-cyclinA, CDK2-cyclinE, CDK4-cyclinD1, CDK5-p35, respectively. Indirubin-3'-monoxime is a direct and selective 5-lipoxygenase inhibitor with IC50 of 7.8-10 μM.

Storage Conditions

3 years -20°C powder

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