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VU-29

Product Specifications

CAS Number

890764-36-0

Target

GluR

Applications

Neuronal Signaling

Smiles

[O-][N+] (=O) C1=CC=C (C=C1) C (=O) NC2=CC (=N[N]2C3=CC=CC=C3) C4=CC=CC=C4

Molecular Formula

C22H16N4O3

Additionnal Information

VU-29 is a positive allosteric modulator of metabotropic glutamate 5 (mGlu5) receptor, with EC50 of 9 nM and Ki=244 nM for rat mGluR5, which is selective for mGluR5 relative to other mGluR subtypes.

Storage Conditions

3 years -20°C powder

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