Simvastatin
Product Specifications
CAS Number
79902-63-9
Synonyms
MK 733
Target
HMG-CoA Reductase
Applications
Metabolism
Smiles
CCC (C) (C) C (=O) OC1CC (C=C2C1C (C (C=C2) C) CCC3CC (CC (=O) O3) O) C
Molecular Formula
C25H38O5
Additionnal Information
Simvastatin is a competitive inhibitor of HMG-CoA reductase with Ki of 0.1-0.2 nM in cell-free assays. Simvastatin induces ferroptosis, mitophagy, autophagy and apoptosis.
Storage Conditions
2 years -80 in solvent
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