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Thioguanine

Product Specifications

CAS Number

154-42-7

Synonyms

NSC 752, 6-Thioguanine, 2-Amino-6-purinethiol

Target

DNA Methyltransferase

Applications

Epigenetics

Smiles

C1=NC2=C (N1) C (=S) N=C (N2) N

Molecular Formula

C5H5N5S

Additionnal Information

Thioguanine, a purine antimetabolite, inhibits DNMT1 activity through ubiquitin-targeted degradation, used in the treatment of acute lymphoblastic leukemia, autoimmune disorders (e.g., Crohn's disease, rheumatoid arthritis) and organ transplant recipients.

Storage Conditions

2 years -80 in solvent

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