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KU-60019

Product Specifications

CAS Number

925701-49-1

Target

ATM/ATR

Applications

PI3K/Akt/mTOR

Smiles

CC1CN (CC (O1) C) CC (=O) NC2=CC3=C (C=C2) SC4=C (C3) C=CC=C4C5=CC (=O) C=C (O5) N6CCOCC6

Molecular Formula

C30H33N3O5S

Additionnal Information

KU-60019 is an improved analogue of KU-55933, with IC50 of 6.3 nM for ATM in cell-free assays, 270- and 1600-fold more selective for ATM than DNA-PK and ATR, and is a highly effective radiosensitizer.

Storage Conditions

2 years -80 in solvent

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