KU-60019
Product Specifications
CAS Number
925701-49-1
Target
ATM/ATR
Applications
PI3K/Akt/mTOR
Smiles
CC1CN (CC (O1) C) CC (=O) NC2=CC3=C (C=C2) SC4=C (C3) C=CC=C4C5=CC (=O) C=C (O5) N6CCOCC6
Molecular Formula
C30H33N3O5S
Additionnal Information
KU-60019 is an improved analogue of KU-55933, with IC50 of 6.3 nM for ATM in cell-free assays, 270- and 1600-fold more selective for ATM than DNA-PK and ATR, and is a highly effective radiosensitizer.
Storage Conditions
2 years -80 in solvent
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