Pomalidomide
Product Specifications
CAS Number
19171-19-8
Synonyms
CC-4047
Target
TNF-alpha
Applications
Apoptosis
Smiles
C1CC (=O) NC (=O) C1N2C (=O) C3=C (C2=O) C (=CC=C3) N
Molecular Formula
C13H11N3O4
Additionnal Information
Pomalidomide inhibits LPS-induced TNF-α release with IC50 of 13 nM in PBMCs. Pomalidomide can be utilized in PROTAC as a ligand for targeting E3 ligase and inhibiting the E3 ligase protein cereblon (CRBN) . Pomalidomide promotes apoptosis and cell cycle arrest.
Storage Conditions
2 years -80 in solvent
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