Adavosertib (MK-1775)
Product Specifications
CAS Number
955365-80-7
Synonyms
AZD1775
Target
Wee1
Applications
Cell Cycle
Smiles
CC (C) (C1=NC (=CC=C1) N2C3=NC (=NC=C3C (=O) N2CC=C) NC4=CC=C (C=C4) N5CCN (CC5) C) O
Molecular Formula
C27H32N8O2
Additionnal Information
Adavosertib (MK-1775, AZD1775) is a potent and selective Wee1 inhibitor with IC50 of 5.2 nM in a cell-free assay; hinders G2 DNA damage checkpoint. Phase 2.
Storage Conditions
2 years -80 in solvent
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