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AT7519

Product Specifications

CAS Number

844442-38-2

Synonyms

AT7519M

Target

CDK

Applications

Cell Cycle

Smiles

C1CNCCC1NC (=O) C2=C (C=NN2) NC (=O) C3=C (C=CC=C3Cl) Cl

Molecular Formula

C16H17Cl2N5O2

Additionnal Information

AT7519 is a multi-CDK inhibitor for CDK1, 2, 4, 6 and 9 with IC50 of 10-210 nM. It is less potent to CDK3 and little active to CDK7. AT7519 also decrease GSK3β phosphorylation. AT7519 induces apoptosis. Phase 2.

Storage Conditions

2 years -80 in solvent

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