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Pralatrexate

Product Specifications

CAS Number

146464-95-1

Synonyms

NSC 754230

Target

DHFR

Applications

Cell Cycle

Smiles

C#CCC (CC1=CN=C2C (=N1) C (=NC (=N2) N) N) C3=CC=C (C=C3) C (=O) NC (CCC (=O) O) C (=O) O

Molecular Formula

C23H23N7O5

Additionnal Information

Pralatrexate is an antifolate, and structurally a folate analog. Its IC50 is < 300 nM in some cell lines. Pralatrexate induces tumor cell apoptosis.

Storage Conditions

2 years -80 in solvent

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