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SB525334

Product Specifications

CAS Number

356559-20-1

Target

TGF-beta/Smad

Applications

TGF-beta/Smad

Smiles

CC1=NC (=CC=C1) C2=C (N=C (N2) C (C) (C) C) C3=CC4=NC=CN=C4C=C3

Molecular Formula

C21H21N5

Additionnal Information

SB525334 is a potent and selective inhibitor of TGFβ receptor I (ALK5) with IC50 of 14.3 nM in a cell-free assay, 4-fold less potent to ALK4 than ALK5 and inactive to ALK2, 3, and 6.

Storage Conditions

2 years -80 in solvent

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