Tipifarnib
Product Specifications
CAS Number
192185-72-1
Synonyms
R115777, IND 58359
Target
Transferase
Applications
Metabolism
Smiles
CN1C=NC=C1C (C2=CC=C (C=C2) Cl) (C3=CC4=C (C=C3) N (C (=O) C=C4C5=CC (=CC=C5) Cl) C) N
Molecular Formula
C27H22Cl2N4O
Additionnal Information
Tipifarnib is a potent and specific farnesyltransferase (FTase) inhibitor with IC50 of 0.6 nM, its anti-proliferative effects are most prominent in H-ras or N-ras mutant cells. Phase 3.
Storage Conditions
2 years -80 in solvent
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