TCS7010 (Aurora A Inhibitor I)
Product Specifications
CAS Number
1158838-45-9
Synonyms
TC-S 7010
Target
Aurora Kinase
Applications
Cell Cycle
Smiles
CCN1CCN (CC1) C (=O) CC2=CC=C (C=C2) NC3=NC=C (C (=N3) NC4=CC=C (C=C4) C (=O) NC5=CC=CC=C5Cl) F
Molecular Formula
C31H31ClFN7O2
Additionnal Information
TCS7010 (Aurora A Inhibitor I) is a novel, potent, and selective inhibitor of Aurora A with IC50 of 3.4 nM in a cell-free assay. It is 1000-fold more selective for Aurora A than Aurora B. Aurora A Inhibitor I (TC-S 7010) triggers apoptosis through the ROS-mediated UPR signaling pathway.
Storage Conditions
2 years -80 in solvent
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