Mizoribine
Product Specifications
CAS Number
50924-49-7
Synonyms
NSC 289637, HE 69
Target
DNA/RNA Synthesis
Applications
Cell Cycle
Smiles
C1=NC (=C (N1C2C (C (C (O2) CO) O) O) O) C (=O) N
Molecular Formula
C9H13N3O6
Additionnal Information
Mizoribine is an imidazole nucleoside and an immunosuppressant that inhibits HCV RNA replication with IC50 of ~ 100 μM for anti-HCV activity. Mizoribine is a selective inhibitor of inosine-5'-monophosphate dehydrogenase (IMPDH) and guanosine monophosphate synthetase. Mizoribine also inhibits SARS-CoV.
Storage Conditions
2 years -80 in solvent
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