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Ketoconazole

Product Specifications

CAS Number

65277-42-1

Synonyms

R 41400

Target

P450 (e.g. CYP17)

Applications

Metabolism

Smiles

CC (=O) N1CCN (CC1) C2=CC=C (C=C2) OCC3COC (O3) (CN4C=CN=C4) C5=C (C=C (C=C5) Cl) Cl

Molecular Formula

C26H28Cl2N4O4

Additionnal Information

Ketoconazole inhibits cyclosporine oxidase and testosterone 6 beta-hydroxylase with IC50 of 0.19 mM and 0.22 mM, respectively. Ketoconazole is an androgen biosynthesis inhibitor.

Storage Conditions

2 years -80 in solvent

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