Floxuridine (FUDR)
Product Specifications
CAS Number
50-91-9
Synonyms
NSC 27640, Deoxyfluorouridine
Target
DNA/RNA Synthesis
Applications
Cell Cycle
Smiles
C1C (C (OC1N2C=C (C (=O) NC2=O) F) CO) O
Molecular Formula
C9H11FN2O5
Additionnal Information
Floxuridine (FUDR) is a prodrug that is rapidly catabolized to 5-fluorouracil in vivo. Floxuridine is used to treat various cancers, particularly metastases to the liver. Floxuridine inhibits Poly (ADP-Ribose) polymerase and induces DNA damage and apoptosis. Floxuridine has antiviral effects against HSV and CMV.
Storage Conditions
2 years -80 in solvent
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