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Camptothecin (CPT)

Product Specifications

CAS Number

7689-03-4

Synonyms

Campathecin, (S) - (+) -Camptothecin, NSC-100880

Target

Topoisomerase

Applications

DNA Damage/DNA Repair

Smiles

CCC1 (C2=C (COC1=O) C (=O) N3CC4=CC5=CC=CC=C5N=C4C3=C2) O

Molecular Formula

C20H16N2O4

Additionnal Information

Camptothecin (CPT) is a specific inhibitor of DNA topoisomerase I (Topo I) with IC50 of 0.68 μM in a cell-free assay. Camptothecin induces apoptosis in cancer cells via microRNA-125b-mediated mitochondrial pathways. Phase 2.

Storage Conditions

2 years -80 in solvent

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