Laduviglusib (CHIR-99021)
Product Specifications
CAS Number
252917-06-9
Synonyms
CT99021
Target
GSK-3
Applications
PI3K/Akt/mTOR
Smiles
CC1=CN=C (N1) C2=CN=C (N=C2C3=C (C=C (C=C3) Cl) Cl) NCCNC4=NC=C (C=C4) C#N
Molecular Formula
C22H18Cl2N8
Additionnal Information
Laduviglusib (CHIR-99021, CT99021) is a GSK-3α and GSK-3β inhibitor with IC50 of 10 nM and 6.7 nM, respectively. CHIR99201 does not exhibit cross-reactivity against cyclin-dependent kinases (CDKs) and shows a 350-fold selectivity toward GSK-3β compared to CDKs. CHIR99021 functions as a Wnt/β-catenin activator and induces autophagy.
Storage Conditions
2 years -80 in solvent
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
AP32277FC-N 1 mg
Mouse IgA (alpha chain specific) Goat Polyclonal Antibody
Sign In for Pricing
View Details 
![VILIP1 (VSNL1) Mouse Monoclonal Antibody (HRP conjugated) [Clone ID: OTI6E1]](https://cdn.genprice.uk/products/937/68dd1b77061270361ea1ad8a/imageurl/ta801991bm.webp)
TA801991BM 100 µL
VILIP1 (VSNL1) Mouse Monoclonal Antibody (HRP conjugated) [Clone ID: OTI6E1]
Sign In for Pricing
View Details