Posaconazole
Product Specifications
CAS Number
171228-49-2
Synonyms
SCH 56592, POS
Target
P450 (e.g. CYP17)
Applications
Metabolism
Smiles
CCC (C (C) O) N1C (=O) N (C=N1) C2=CC=C (C=C2) N3CCN (CC3) C4=CC=C (C=C4) OCC5CC (OC5) (CN6C=NC=N6) C7=C (C=C (C=C7) F) F
Molecular Formula
C37H42F2N8O4
Additionnal Information
Posaconazole is an inhibitor primarily of CYP3A4, but it does not inhibit the activity of other CYP enzymes; Also an inhibitor of sterol C14ɑ demethylase inhibitor with IC50 of 0.25 μM. Posaconazole has a median terminal elimination half-life of 15-35 hours.
Storage Conditions
2 years -80 in solvent
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