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2-Methoxyestradiol (2-MeOE2)

Product Specifications

CAS Number

362-07-2

Synonyms

NSC 659853, 2-ME2

Target

HIF

Applications

Angiogenesis

Smiles

CC12CCC3C (C1CCC2O) CCC4=CC (=C (C=C34) OC) O

Molecular Formula

C19H26O3

Additionnal Information

2-Methoxyestradiol (2-MeOE2, NSC 659853, 2-ME2) depolymerizes microtubules and blocks HIF-1α nuclear accumulation and HIF-transcriptional activity. 2-Methoxyestradiol induces both autophagy and apoptosis in various carcinogenic cell lines.

Storage Conditions

2 years -80 in solvent

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