Clofarabine
Product Specifications
CAS Number
123318-82-1
Synonyms
Clolar
Target
DNA/RNA Synthesis
Applications
Cell Cycle
Smiles
C1=NC2=C (N=C (N=C2N1C3C (C (C (O3) CO) O) F) Cl) N
Molecular Formula
C10H11ClFN5O3
Additionnal Information
Clofarabine (Clolar) inhibits the enzymatic activities of ribonucleotide reductase (RNR) (IC50 = 65 nM) and DNA polymerase. Clofarabine induces autophagy and apoptosis.
Storage Conditions
2 years -80 in solvent
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