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PFI-1 (PF-6405761)

Product Specifications

CAS Number

1403764-72-6

Target

Epigenetic Reader Domain

Applications

Epigenetics

Smiles

CN1CC2=C (C=CC (=C2) NS (=O) (=O) C3=CC=CC=C3OC) NC1=O

Molecular Formula

C16H17N3O4S

Additionnal Information

PFI-1 (PF-6405761) is a highly selective BET (bromodomain-containing protein) inhibitor for BRD4 with IC50 of 0.22 μM and for BRD2 with IC50 of 98 nM in a cell-free assay.

Storage Conditions

2 years -80 in solvent

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