Carboplatin

Product Specifications

CAS Number

41575-94-4

Synonyms

NSC 241240, JM-8, CBDCA

Target

DNA/RNA Synthesis

Applications

Cell Cycle

Smiles

C1CC (C1) (C (=O) O) C (=O) O.[NH2-].[NH2-].[Pt+2]

Molecular Formula

C6H12N2O4Pt

Additionnal Information

Carboplatin, a derivative of CDDP, is a DNA synthesis inhibitor which binds to DNA, inhibits replication and transcription and induces cell death and interfers with the cell's repair mechanism in A2780, SKOV-3, IGROV-1, and HX62 cells. It induces the formation of DNA interstrand crosslinks and DNA-protein crosslinks. Solutions are unstable and should be fresh-prepared.DMSO is not recommended to dissolve platinum-based drugs, which can easily lead to drug inactivation.