Doxorubicin (DOX) HCl
Product Specifications
CAS Number
25316-40-9
Synonyms
Adriamycin, NSC 123127, Hydroxydaunorubicin HCl
Target
Topoisomerase
Applications
DNA Damage/DNA Repair
Smiles
CC1C (C (CC (O1) OC2CC (CC3=C2C (=C4C (=C3O) C (=O) C5=C (C4=O) C (=CC=C5) OC) O) (C (=O) CO) O) N) O.Cl
Molecular Formula
C27H29NO11.HCl
Additionnal Information
Doxorubicin (DOX) HCl is an antibiotic agent that inhibits human DNA topoisomerase I and topoisomerase II with IC50s of 0.8 μM and 2.67 μM, respectively. Doxorubicin reduces basal phosphorylation of AMPK. Doxorubicin is used in the concomitant treatment of HIV-infected patients but is found to be at high risk of HBV reactivation.This product may precipitate when dissolved in PBS solution. It is recommended to prepare the stock solution in pure water and dilute with either pure water or saline to obtain the working solution.Doxorubicin (Adriamycin) HCl can be used to induce animal models of kidney disease.
Storage Conditions
2 years -80 in solvent
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
041922 1 Pack (1 Label x 1 Pack)
BLANK YELLOW UTILITY TAG 1.5x3 Blank General Purpose Tags
Sign In for Pricing
View Details MBS2137871-01 0.1 mL
FITC Linked Monoclonal Antibody to Wingless Type MMTV Integration Site Family, Member 4 (WNT4)
Sign In for Pricing
View Details MBS2137871-02 0.2 mL
FITC Linked Monoclonal Antibody to Wingless Type MMTV Integration Site Family, Member 4 (WNT4)
Sign In for Pricing
View Details MBS2137871-03 0.5 mL
FITC Linked Monoclonal Antibody to Wingless Type MMTV Integration Site Family, Member 4 (WNT4)
Sign In for Pricing
View Details MBS2137871-04 1 mL
FITC Linked Monoclonal Antibody to Wingless Type MMTV Integration Site Family, Member 4 (WNT4)
Sign In for Pricing
View Details