BIBR 1532
Product Specifications
CAS Number
321674-73-1
Target
Telomerase
Applications
DNA Damage/DNA Repair
Smiles
CC (=CC (=O) NC1=CC=CC=C1C (=O) O) C2=CC3=CC=CC=C3C=C2
Molecular Formula
C21H17NO3
Additionnal Information
BIBR 1532 is a potent, selective, non-competitive telomerase inhibitor with IC50 of 100 nM in a cell-free assay. No inhibition of DNA and RNA polymerases, including HIV reverse transcriptase are observed at concentrations vastly exceeding the IC50 for telomerase. BIBR 1532 induces apoptosis in cancer cells.
Storage Conditions
2 years -80 in solvent
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