PD98059
Product Specifications
CAS Number
167869-21-8
Target
MEK
Applications
Protein Tyrosine Kinase
Smiles
COC1=CC=CC (=C1N) C2=CC (=O) C3=CC=CC=C3O2
Molecular Formula
C16H13NO3
Additionnal Information
PD98059 is a non-ATP competitive MEK inhibitor with IC50 of 2 μM in a cell-free assay, specifically inhibits MEK-1-mediated activation of MAPK; does not directly inhibit ERK1 or ERK2. PD98059 is a ligand for the aryl hydrocarbon receptor (AHR) and functions as an AHR antagonist.
Storage Conditions
2 years -80 in solvent
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