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Serdemetan (JNJ-26854165)

Product Specifications

CAS Number

881202-45-5

Target

E3 Ligase

Applications

Ubiquitin

Smiles

C1=CC=C2C (=C1) C (=CN2) CCNC3=CC=C (C=C3) NC4=CC=NC=C4

Molecular Formula

C21H20N4

Additionnal Information

Serdemetan (JNJ-26854165) acts as a HDM2 ubiquitin ligase antagonist and also induces early apoptosis in p53 wild-type cells, inhibits cellular proliferation followed by delayed apoptosis in the absence of functional p53. Phase 1.

Storage Conditions

2 years -80 in solvent

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