Valproic Acid sodium

Product Specifications

CAS Number

1069-66-5

Synonyms

Sodium valproate, NSC 93819,2-Propylpentanoic Acid

Target

GABA Receptor

Applications

Neuronal Signaling

Smiles

CCCC (CCC) C (=O) [O-].[Na+]

Molecular Formula

C8H15NaO2

Additionnal Information

Valproic Acid sodium is a HDAC inhibitor by selectively inducing proteasomal degradation of HDAC2, used in the treatment of epilepsy, bipolar disorder and prevention of migraine headaches. Valproic acid induces Notch1 signaling in small cell lung cancer (SCLC) cells. Valproic acid is under investigation for treatment of HIV and various cancers. Valproic acid (VPA) induces autophagy and mitophagy by upregulation of BNIP3 and mitochondrial biogenesis by upregulating PGC-1α.