Valproic Acid sodium
Product Specifications
CAS Number
1069-66-5
Synonyms
Sodium valproate, NSC 93819,2-Propylpentanoic Acid
Target
GABA Receptor
Applications
Neuronal Signaling
Smiles
CCCC (CCC) C (=O) [O-].[Na+]
Molecular Formula
C8H15NaO2
Additionnal Information
Valproic Acid sodium is a HDAC inhibitor by selectively inducing proteasomal degradation of HDAC2, used in the treatment of epilepsy, bipolar disorder and prevention of migraine headaches. Valproic acid induces Notch1 signaling in small cell lung cancer (SCLC) cells. Valproic acid is under investigation for treatment of HIV and various cancers. Valproic acid (VPA) induces autophagy and mitophagy by upregulation of BNIP3 and mitochondrial biogenesis by upregulating PGC-1α.
Storage Conditions
2 years -80 in solvent
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