SNS-314
Product Specifications
CAS Number
1057249-41-8
Target
Aurora Kinase
Applications
Cell Cycle
Smiles
C1=CC (=CC (=C1) Cl) NC (=O) NC2=NC=C (S2) CCNC3=NC=NC4=C3SC=C4
Molecular Formula
C18H15ClN6OS2
Additionnal Information
SNS-314 is a potent and selective inhibitor of Aurora A, Aurora B and Aurora C with IC50 of 9 nM, 31 nM, and 3 nM, respectively. It is less potent to Trk A/B, Flt4, Fms, Axl, c-Raf and DDR2. Phase 1.
Storage Conditions
2 years -80 in solvent
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