Roscovitine

Product Specifications

CAS Number

186692-46-6

Synonyms

CYC202, Seliciclib, R-roscovitine

Target

CDK

Applications

Cell Cycle

Smiles

CCC (CO) NC1=NC (=C2C (=N1) N (C=N2) C (C) C) NCC3=CC=CC=C3

Molecular Formula

C19H26N6O

Additionnal Information

Roscovitine is a potent and selective CDK inhibitor for Cdc2, CDK2 and CDK5 with IC50 of 0.65 μM, 0.7 μM and 0.16 μM in cell-free assays. It shows little effect on CDK4/6. Phase 2.

Storage Conditions

2 years -80 in solvent

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