PLX-4720
Product Specifications
CAS Number
918505-84-7
Target
Raf
Applications
MAPK
Smiles
CCCS (=O) (=O) NC1=C (C (=C (C=C1) F) C (=O) C2=CNC3=C2C=C (C=N3) Cl) F
Molecular Formula
C17H14ClF2N3O3S
Additionnal Information
PLX4720 is a potent and selective inhibitor of B-RafV600E with IC50 of 13 nM in a cell-free assay, equally potent to c-Raf-1 (Y340D and Y341D mutations), 10-fold selectivity for B-RafV600E than wild-type B-Raf.
Storage Conditions
2 years -80 in solvent
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