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Barasertib (AZD1152-HQPA)

Product Specifications

CAS Number

722544-51-6

Synonyms

AZD2811, INH-34, Barasertib-HQPA , Defosbarasertib

Target

Aurora Kinase

Applications

Cell Cycle

Smiles

CCN (CCCOC1=CC2=C (C=C1) C (=NC=N2) NC3=NNC (=C3) CC (=O) NC4=CC (=CC=C4) F) CCO

Molecular Formula

C26H30FN7O3

Additionnal Information

Defosbarasertib (AZD1152-HQPA, AZD2811, INH-34, Barasertib-HQPA) is a highly selective Aurora B inhibitor with IC50 of 0.37 nM in a cell-free assay, ~3700 fold more selective for Aurora B over Aurora A. Phase 1.

Storage Conditions

2 years -80 in solvent

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