Ivacaftor (VX-770)
Product Specifications
CAS Number
873054-44-5
Synonyms
VX-770
Target
CFTR
Applications
Transmembrane Transporters
Smiles
CC (C) (C) C1=CC (=C (C=C1NC (=O) C2=CNC3=CC=CC=C3C2=O) O) C (C) (C) C
Molecular Formula
C24H28N2O3
Additionnal Information
Ivacaftor (VX-770) is a selective potentiator of CFTR targeting G551D-CFTR and F508del-CFTR with EC50 of 100 nM and 25 nM in fisher rat thyroid cells, respectively.
Storage Conditions
2 years -80 in solvent
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