Pemetrexed disodium
Product Specifications
CAS Number
150399-23-8
Synonyms
LY-231514 disodium
Target
DHFR
Applications
Cell Cycle
Smiles
C1=CC (=CC=C1CCC2=CNC3=C2C (=O) NC (=N3) N) C (=O) NC (CCC (=O) [O-]) C (=O) [O-].[Na+].[Na+]
Molecular Formula
C20H19N5Na2O6
Additionnal Information
Pemetrexed disodium is a novel antifolate and antimetabolite for TS, DHFR and GARFT with Ki of 1.3 nM, 7.2 nM and 65 nM in cell-free assays, respectively. Pemetrexed induces autophagy and apoptosis.
Storage Conditions
2 years -80 in solvent
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