BMS-754807
Product Specifications
CAS Number
1001350-96-4
Target
C-Met
Applications
Protein Tyrosine Kinase
Smiles
CC1 (CCCN1C2=NN3C=CC=C3C (=N2) NC4=NNC (=C4) C5CC5) C (=O) NC6=CN=C (C=C6) F
Molecular Formula
C23H24FN9O
Additionnal Information
BMS-754807 is a potent and reversible inhibitor of IGF-1R/InsR with IC50 of 1.8 nM/1.7 nM in cell-free assays, less potent to Met (c-Met), Aurora A/B, TrkA/B and Ron, and shows little activity to Flt3, Lck, MK2, PKA, PKC etc. Phase 2.
Storage Conditions
2 years -80 in solvent
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