What is the catalog number for Cabozantinib (XL184)?

The catalog number for Cabozantinib (XL184) is S1119-50mg.

What sizes are available for Cabozantinib (XL184)?

Cabozantinib (XL184) is available in the following size(s): 50 mg.

Is Cabozantinib (XL184) in stock?

Cabozantinib (XL184) is currently made to order / not held in immediate stock. Contact us for lead time.

Are there any special shipping requirements for Cabozantinib (XL184)?

Cabozantinib (XL184) is requires dry ice shipping.

Who manufactures Cabozantinib (XL184)?

Cabozantinib (XL184) is manufactured by Bimake.

What is the estimated delivery time for Cabozantinib (XL184)?

Estimated delivery time for Cabozantinib (XL184) is approximately 15 business day(s), depending on your location.

Cabozantinib (XL184)

Product Specifications

CAS Number

849217-68-1

Synonyms

BMS-907351

Target

C-Met

Applications

Protein Tyrosine Kinase

Smiles

COC1=CC2=C (C=CN=C2C=C1OC) OC3=CC=C (C=C3) NC (=O) C4 (CC4) C (=O) NC5=CC=C (C=C5) F

Molecular Formula

C28H24FN3O5

Additionnal Information

Cabozantinib (XL184) is a potent VEGFR2 inhibitor with IC50 of 0.035 nM and also inhibits c-Met, Ret, Kit, Flt-1/3/4, Tie2, and AXL with IC50 of 1.3 nM, 4 nM, 4.6 nM, 12 nM/11.3 nM/6 nM, 14.3 nM and 7 nM in cell-free assays, respectively. Cabozantinib induces PUMA-dependent apoptosis in colon cancer cells via AKT/GSK-3β/NF-κB signaling pathway.