BI 2536
Product Specifications
CAS Number
755038-02-9
Target
PLK
Applications
Cell Cycle
Smiles
CCC1C (=O) N (C2=CN=C (N=C2N1C3CCCC3) NC4=C (C=C (C=C4) C (=O) NC5CCN (CC5) C) OC) C
Molecular Formula
C28H39N7O3
Additionnal Information
BI-2536 is a potent Plk1 inhibitor with IC50 of 0.83 nM in a cell-free assay. BI-2536 inhibits Bromodomain 4 (BRD4) with Kd of 37 nM and potently suppresses c-Myc expression. BI-2536 induces apoptosis and attenuates autophagy. Phase 2.
Storage Conditions
2 years -80 in solvent
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
K0199-08X 50 µg
Keratin 8, 18,19 (Keratin Type II Cytoskeletal 8, Keratin 8, Keratin-8, K8, KRT8, Keratin Type I Cytoskeletal 18, Keratin 18, Keratin-18, K18, KRT18, CARD2, Cell Proliferation-inducing Gene 46 Protein, Cytokeratin-8, CK8, CK-8, CYK8, Cytokeratin-18, CK-18, CYK18, K2C8, KO, PIG46, Type-II Keratin Kb8, Keratin, Type I Cytoskeletal 19, Cytokeratin-19, CK-19, Keratin-19, K19, KRT19) discontinued
Sign In for Pricing
View Details 
E-PP-0758-01 10 mg
BFGF (119-126), Basic Fibroblast Growth Factor, human, bovine
Sign In for Pricing
View Details E-PP-0758-02 100 mg
BFGF (119-126), Basic Fibroblast Growth Factor, human, bovine
Sign In for Pricing
View Details E-PP-0758-03 5 mg
BFGF (119-126), Basic Fibroblast Growth Factor, human, bovine
Sign In for Pricing
View Details