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OSU-03012 (AR-12)

Product Specifications

CAS Number

742112-33-0

Target

PDPK1

Applications

PI3K/Akt/mTOR

Smiles

C1=CC=C2C (=C1) C=CC3=C2C=CC (=C3) C4=CC (=NN4C5=CC=C (C=C5) NC (=O) CN) C (F) (F) F

Molecular Formula

C26H19F3N4O

Additionnal Information

OSU-03012 (AR-12) is a potent inhibitor of recombinant PDK-1 (phosphoinositide-dependent kinase 1) with IC50 of 5 μM in a cell-free assay and 2-fold increase in potency over OSU-02067.

Storage Conditions

2 years -80 in solvent

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