What is the catalog number for LY294002?

The catalog number for LY294002 is S1105-1g.

What sizes are available for LY294002?

LY294002 is available in the following size(s): 1 g.

Is LY294002 in stock?

LY294002 is currently made to order / not held in immediate stock. Contact us for lead time.

Are there any special shipping requirements for LY294002?

LY294002 is requires dry ice shipping.

Who manufactures LY294002?

LY294002 is manufactured by Bimake.

What is the estimated delivery time for LY294002?

Estimated delivery time for LY294002 is approximately 15 business day(s), depending on your location.

LY294002

Product Specifications

CAS Number

154447-36-6

Synonyms

SF 1101, NSC 697286

Target

Autophagy

Applications

Autophagy

Smiles

C1COCCN1C2=CC (=O) C3=C (O2) C (=CC=C3) C4=CC=CC=C4

Molecular Formula

C19H17NO3

Additionnal Information

LY294002 (SF 1101, NSC 697286) is the first synthetic molecule known to inhibit PI3Kα/δ/β with IC50 of 0.5 μM/0.57 μM/0.97 μM, respectively; more stable in solution than Wortmannin, and also blocks autophagosome formation. It not only binds to class I PI3Ks and other PI3K-related kinases, but also to novel targets seemingly unrelated to the PI3K family. LY294002 also inhibits CK2 with IC50 of 98 nM. LY294002 is a non-specific DNA-PKcs inhibitor and activates autophagy and apoptosis.