GDC-0879

Product Specifications

CAS Number

905281-76-7

Synonyms

AR-00341677

Target

Raf

Applications

MAPK

Smiles

C1CC (=NO) C2=C1C=C (C=C2) C3=CN (N=C3C4=CC=NC=C4) CCO

Molecular Formula

C19H18N4O2

Additionnal Information

GDC-0879 (AR-00341677) is a novel, potent, and selective B-Raf inhibitor with IC50 of 0.13 nM in A375 and Colo205 cells with activity against c-Raf as well; no inhibition known to other protein kinases.

Storage Conditions

2 years -80 in solvent

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