ZM 447439
Product Specifications
CAS Number
331771-20-1
Target
Aurora Kinase
Applications
Cell Cycle
Smiles
COC1=C (C=C2C (=C1) C (=NC=N2) NC3=CC=C (C=C3) NC (=O) C4=CC=CC=C4) OCCCN5CCOCC5
Molecular Formula
C29H31N5O4
Additionnal Information
ZM 447439 is a selective and ATP-competitive inhibitor for Aurora A and Aurora B with IC50 of 110 nM and 130 nM, respectively. It is more than 8-fold selective for Aurora A/B than MEK1, Src, Lck and has little effect against CDK1/2/4, Plk1, Chk1, etc.
Storage Conditions
2 years -80 in solvent
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
MBS6158156-01 0.1 mL
HDGFRP3 (HDGF2, Hepatoma-derived Growth Factor-related Protein 3, HRP-3, Hepatoma-derived Growth Factor 2, HDGF-2, CGI-142) (PE)
Sign In for Pricing
View Details MBS6158156-02 5x 0.1 mL
HDGFRP3 (HDGF2, Hepatoma-derived Growth Factor-related Protein 3, HRP-3, Hepatoma-derived Growth Factor 2, HDGF-2, CGI-142) (PE)
Sign In for Pricing
View Details MBS2163327-01 0.1 mL
APC_Cy7-Linked Monoclonal Antibody to Family With Sequence Similarity 20, Member A (FAM20A)
Sign In for Pricing
View Details MBS2163327-02 0.2 mL
APC_Cy7-Linked Monoclonal Antibody to Family With Sequence Similarity 20, Member A (FAM20A)
Sign In for Pricing
View Details