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Rucaparib phosphate

Product Specifications

CAS Number

459868-92-9

Synonyms

AG-014699 phosphate, PF-01367338 phosphate

Target

PARP

Applications

DNA Damage/DNA Repair

Smiles

CNCC1=CC=C (C=C1) C2=C3CCNC (=O) C4=C3C (=CC (=C4) F) N2.OP (=O) (O) O

Molecular Formula

C19H18FN3O.H3PO4

Additionnal Information

Rucaparib phosphate is an inhibitor of PARP with Ki of 1.4 nM for PARP1 in a cell-free assay, also showing binding affinity to eight other PARP domains. Phase 3.

Storage Conditions

2 years -80 in solvent

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