Quisinostat (JNJ-26481585) 2HCl
Product Specifications
CAS Number
875320-31-3
Target
HDAC
Applications
DNA Damage/DNA Repair
Smiles
CN1C=C (C2=CC=CC=C21) CNCC3CCN (CC3) C4=NC=C (C=N4) C (=O) NO.Cl.Cl
Molecular Formula
C21H28Cl2N6O2
Additionnal Information
Quisinostat (JNJ-26481585) 2HCl is a novel second-generation HDAC inhibitor with highest potency for HDAC1 with IC50 of 0.11 nM in a cell-free assay, modest potent to HDACs 2, 4, 10, and 11; greater than 30-fold selectivity against HDACs 3, 5, 8, and 9 and lowest potency to HDACs 6 and 7. Phase 2.
Storage Conditions
2 years -80 in solvent
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