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PF-04217903

Product Specifications

CAS Number

956905-27-4

Target

C-Met

Applications

Protein Tyrosine Kinase

Smiles

C1=CC2=C (C=CC (=C2) CN3C4=NC (=CN=C4N=N3) C5=CN (N=C5) CCO) N=C1

Molecular Formula

C19H16N8O

Additionnal Information

PF-04217903 is a selective ATP-competitive c-Met inhibitor with IC50 of 4.8 nM in A549 cell line, susceptible to oncogenic mutations (no activity to Y1230C mutant) . Phase 1.

Storage Conditions

2 years -80 in solvent

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