KU-55933
Product Specifications
CAS Number
587871-26-9
Synonyms
ATM Kinase Inhibitor
Target
ATM/ATR
Applications
PI3K/Akt/mTOR
Smiles
C1COCCN1C2=CC (=O) C=C (O2) C3=C4C (=CC=C3) SC5=CC=CC=C5S4
Molecular Formula
C21H17NO3S2
Additionnal Information
KU-55933 is a potent and specific ATM inhibitor with IC50/Ki of 12.9 nM/2.2 nM in cell-free assays, and is highly selective for ATM as compared to DNA-PK, PI3K/PI4K, ATR and mTOR. KU‐55933 (ATM Kinase Inhibitor) inhibits the activation of autophagy‐initiating kinase ULK1 and results in a significant decrease of autophagy.
Storage Conditions
2 years -80 in solvent
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